Research Updates

We have submitted an application and have been given tentative approval by the FDA to conduct trials in people with stomach, intestinal, and colon cancers that have spread to the liver and who have no hope for a cure. We are nearly finished with the additional studies that were requested in the FDA response and are in the process of answering the questions in a report that should be completed by the end of the year.

Submitted for publication August 2007
Attenuated Salmonella typhimurium with IL-2 gene Prevents the Establishment of Pulmonary Metastases in a Model of Osteosarcoma

In addition to our colon cancer model, we have observed a similar reduction in metastases in neuroblastoma and osteogenic sarcoma models. Neuroblastoma is the deadliest solid tumor found in children, so this would be a major advance for children.

October 1, 2007